Figure 1.

Scheme of a C2H2 zinc finger motif. X denotes any amino acid; Z – hydrophobic amino acids [L, I, V, M, F, Y, W, C]; L is Leucine; C is Cysteine; H is Histidine. The binding interface of the α-Helix is formed by amino acids No -1, 1, 2, 3, L, 5 and 6.