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Open AccessShort Communication

Two-stimuli manipulation of a biological motor

Zorica Ristic1 email, Marco Vitali2,5 email, Alessandro Duci3 email, Christian Goetze3 email, Klaus Kemnitz4 email, Werner Zuschratter2 email, Holger Lill1 email and Dirk Bald1 email

Department of Molecular Cell Biology, VU University Amsterdam, Amsterdam, the Netherlands

Leibniz-Institute for Neurobiology, Magdeburg, Germany

arivis Multiple Imaging Tools, Rostock, Germany

EuroPhoton, Berlin, Europhoton, Berlin, Germany

Technical University Berlin, Germany

author email corresponding author email

Journal of Nanobiotechnology 2009, 7:3doi:10.1186/1477-3155-7-3

Published: 15 May 2009

Abstract

F1-ATPase is an enzyme acting as a rotary nano-motor. During catalysis subunits of this enzyme complex rotate relative to other parts of the enzyme. Here we demonstrate that the combination of two input stimuli causes stop of motor rotation. Application of either individual stimulus did not significantly influence motor motion. These findings may contribute to the development of logic gates using single biological motor molecules.


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