Co-localisation of Ru@SiO2-OH and Ru@SiO2-NH2 nanoparticles with early endosomes. Confocal laser scanning microscopy pictures showing a partial co-localisation after 2 h of incubation of Ru@SiO2-OH (A, in red) or Ru@SiO2-NH2 (B, in red) fluorescence with immunosignals for early endosomes protein 1 (A, B, in green). Cell nuclei are stained in blue. Arrows denote large early endosomes, which contain high amounts of nanoparticles. Scale bars = 30 μm.
Besic Gyenge et al. Journal of Nanobiotechnology 2011 9:32 doi:10.1186/1477-3155-9-32